Major Cleaning Expansion Chamber

The wuster column coating System consist of a number
of sections. The filter house, Expansion chamber ,
Wuster column and Product bowl are the key sections.
The expansion chamber provide a space where the
pellet can dry the film of coating solution or suspension
that are sprayed over them.
In the last blog we cover the major cleaning of the
Filter house ,now we are covering the major cleaning of
the Expansion Chamber.
Under cGMP the Expansion Chamber are major cleaned
after the time limitation are expired, Mechanical repair
contaminations,change of active and strength of active.
Each pharmaceutical company have their own SOP
on cleaning the expansion chamber.It is important to read
the SOP on the equipments.
To major clean the expansion chamber ,first take
all safety procedure . Use the high pressure hose to washed
out the debris on the wall of the expansion chamber. Used
hot portable water to continue washing the walls of the
expansion chamber. After used brushes and soap [detergent]
to washed the wall of the expansion chamber.After a thorough
cleaning used portable water to rinse the soap out.Afterward
used purified water to do a final rinse of the wall of the
expansion chamber. After cleaning document in the log book
performed by and checked by.

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